Raphel's Sistine Madonna (1513)
The funny thing about this picture is that the little angels down in the bottom are by far the most famous part of this painting; many people thinking that this is a full painting itself.
Other striking aspects to this painting are the cloth draping shadows and highlights and the colors themselves.
I thought that we would further our look at colors by blending them in a color wheel. We used the page that came with our Renaissance History Portfolio, but you could easily make one by drawing two triangles in the center of two circles as shown below.